Now showing items 1-6 of 6

    • Coarsening dynamics of domains in lipid membranes 

      Stanich, Cynthia Ann (2012-09-13)
      We investigate isothermal diffusion and growth of micron-scale liquid domains within membranes of free-floating giant unilamellar vesicles (GUVs) with diameters between 80µm and 250µm. Domains appear after a rapid temperature ...
    • Investigating Inactive Conformations of Protein Kinases 

      Hari, Sanjay Baju (2013-11-14)
      Protein kinases comprise a substantial fraction of the human genome and constitute a wide array of cell signaling pathways that control countless cellular processes. Improper kinase regulation has been implicated in a ...
    • Relating phase separation and thickness mismatch in model lipid membranes. 

      Bleecker, Joan Vea
      Membrane lipids can spontaneously undergo a process called phase separation wherein they organize into domains with different compositions. Phase separation has been proposed as a mechanism in the formation of heterogeneous ...
    • Solid State NMR Characterization of Biosilicification Peptides 

      Zane, Ariel C. (2013-11-14)
      Biomimetic syntheses of useful inorganic and mineral materials are the subject of much interest in the biomineralization community, as organisms can often produce materials at ambient conditions and temperatures, as opposed ...
    • Sterol-phospholipid interactions in model lipid membranes 

      Litz, Jonathan Paul
      Cell membranes feature complex intermolecular interactions between phospholipids and sterols. In this dissertation, I discuss how the accessibility (a measure of chemical activity) of cholesterol in a lipid bilayer varies ...
    • Structural and biochemical studies of the transcription termination machinery 

      Hsu, Peter (2014-02-24)
      RNA Polymerase II (PolII) dependent transcription of mRNAs is central to gene expression throughout eukaryotes. Transcription is a highly regulated process, with a defined initiation, elongation, and termination phase, all ...