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Taking Artemisinin to Clinical Anticancer Applications: Design, Synthesis and Characterization of pH-responsive Artemisinin Dimer Derivatives in Lipid Nanoparticles
Qinghaosu or Artemisinin is an active sesquiterpene lactone isolated from Artemisia annua L. The natural product and its derivatives are known as a first line treatment for malaria. Investigations have also reported that the compound exhibits anti-cancer activities both on cell lines and in animal models. The remarkably stable ...