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Investigation of the Fundamentals of Electrospray Ionization and the Separation of Small Molecules using Ion Mobility Mass Spectrometry
Ion mobility mass spectrometry (IM-MS) is a gas-phase technique used to separate ions based on their mass-to-charge ratio and collision cross section (i.e. shape). Accurate MS analysis of analytes, such as proteins and protein complexes, relies on the preservation of solution-phase oligomeric distributions during ionization. ...