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Solid-State NMR: investigations of biomolecular structure
Solid-state nuclear magnetic resonance methods were used to characterize the structure of biological molecules in lyophilized and hydrated environments with and without the presence of other molecules such as drugs, lipids, and surfaces. Revealing the structure of biomolecules by mimicking its natural environment, information ...
Synthesis and characterization of annelated nitronyl nitroxides
The heteroaromatic 2'-phenylbenzimidazole 1-nitronyl nitroxide (PBNN), 2'-pyridylbenzimidazole nitronyl nitroxide (2PBNN), 4'-pyridylbenzimidazole nitronyl nitroxide (4PBNN), 2'-thienylbenzimidazole nitronyl nitroxide (2TBNN), and 3'-thienylbenzimidazole nitronyl nitroxide (3TBNN) radicals were synthesized, and the 2-position ...
Spatially and temporally resolved delivery of stimuli to single cells using nanocapsules and laser manipulation
Cell signaling is at the core of most biological processes. The spatially and temporally resolved stimulation will help elucidate cell signaling, and lead us to a better understanding of signal transduction. We have designed and developed a technique to photolyze individual optically trapped nanocontainers for delivering ...