Now showing items 1-2 of 2
Development and Application of Novel Methodologies for the Characterization of Phospholipase A2 Activity: Targeted Lipidomic Profiling and Interfacial Binding Analysis
Phospholipases A2 are a family of enzymes that hydrolyze membrane glycerophospholipids to yield free fatty acids and lysophospholipids. Both products serve as precursors for an array of lipid mediators that play known roles in a variety of signal transduction processes. Discussed herein is the development and application of ...
Bead-based chemistries to quantitate antibody responses to multiple Plasmodium falciparum and Plasmodium vivax antigens
Each year malaria impacts approximately 219 million people and causes over 400,000 deaths. The worldwide parasite burden remains high, even with the availability of efficacious antimalarial drugs and vector control tools such as insecticides and bed nets. Despite large investments in malaria vaccine development, there is ...