Browsing Medicinal chemistry by Author "Kunze, Kent L"
Now showing items 1-2 of 2
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Non-Dissociative Sequential Metabolism of Enoxacin to a Metabolic Intermediate Complex with Cytochrome P450 1A2
Seguin, Ryan PatrickCytochrome P450 enzymes constitute a superfamily of isoforms which accelerate the removal of foreign compounds from the body through oxidative biotransformation to generate polar metabolites that are more readily excreted ... -
Selectivity and Mechanisms of Human Cytochrome P450 Inhibition by Chlormethiazole
Pelletier, Robert DanielThe cytochrome P450 (CYP) superfamily of enzymes are heme containing enzymes that primarily perform oxidative reactions to a variety of substrates, including small molecule drugs and other xenobiotics. Formation of polar ...