Browsing Microbiology by Subject "Theses--Microbiology"
Now showing items 1-9 of 9
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Formaldehyde metabolism in Methylobacterium extorquens AM1
(2003)Methylotrophic bacteria are capable of growth on single-carbon compounds as their sole source of carbon and energy. This metabolism entails the production of formaldehyde as a central intermediate. Methylobacterium extorquens ... -
Host responses to Salmonella typhimurium infection in vitro and in vivo
(2003)Salmonella spp. are facultative intracellular pathogens capable of causing localized and systemic disease of significant morbidity and mortality; disease can be prevented by oral immunization with viable attenuated bacteria. ... -
Identification of factors involved in processing of mRNA in a fimbrial operon of Escherichia coli
(2004)Endonucleolytic cleavage of mRNA in the daa operon of Escherichia coli is responsible for coordinate regulation of genes involved in F1845 fimbrial biogenesis. Cleavage occurs by an unidentified endoribonuclease and ... -
The interferon induced serine/threonine protein kinase, PKR, is regulated by the influenza virus activated protein, P58IPK, and the molecular chaperones, Hsp40 and Hsp70
(1998)P58IPK is a TPR-containing protein with homology to the J-domain of DnaJ. P58IPK was first recognized for its ability to inhibit the interferon-induced double-stranded RNA-activated serine/threonine protein kinase, PKR, ... -
The mechanisms of Pol expression and assembly for human foamy virus
(1999)In this study, I have examined the role of Pol in the replication pathway of HFV. We discovered that unlike all known retroviruses, the Pol protein is expressed independently of Gag from a spliced mRNA, rather than as a ... -
Population genetics of human immunodeficiency virus type 1 during within-host chronic infection
(2003)Human immunodeficiency virus type 1 (HIV-1) has high replication and mutation rates that generate large census populations and high levels of genetic variation. Furthermore, there is now widespread global circulation of ... -
Regulation of protein synthesis and induction of oncogenesis by a cellular protein kinase inhibitor
(1998)P58IPK is a cellular inhibitor of the interferon-induced, dsRNA-activated, serine/threonine kinase, PKR. Earlier, P58IPK was shown to block both PKR autophosphorylation and the phosphorylation of eIF-2alpha substrate in ... -
Regulation of the flagellar specific sigma factor, sigma28, of Salmonella typhimurium by the anti-sigma factor FlgM
(1998)Expression of the flagellar genes of Salmonella typhimurium occurs in an ordered hierarchy that is coupled to the morphogenesis of the flagellar organelle. Transcription of the late (Class 3) flagellar genes is dependent ... -
Taxonomy, biogeography, and evolution of polar gas vacuolate bacteria
(1996)Over 250 gas vesicle producing (gas vacuolate) bacteria have been isolated from arctic and antarctic sea ice and water (Irgens et al., 1989; Staley et al., 1989; Gosink et al., 1993; Gosink and Staley, 1995). These strains ...