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Function, localization and regulation of the Pseudomonas aeruginosa diguanylate cyclase response regulator WspR
WspR is a hybrid response regulator-diguanylate cyclase that is phosphorylated by the Wsp signal transduction complex in response to growth of <italic>Pseudomonas aeruginosa</italic> on surfaces. Active WspR produces c-di-GMP, which in turn stimulates biofilm formation. Previous work demonstrated that when phosphorylated in ...
Posttranslational regulation and effector specificity of the type VI secretion system
Bacteria mediate interactions with their surroundings by exporting a variety of proteins into the extracellular environment. Gram-negative bacteria have evolved at least six dedicated secretory pathways to accomplish this task, each exporting a discrete set of proteins through complex and genetically divergent systems. One ...