Browsing Molecular and cellular biology by Author "Henikoff, Steven"
Now showing items 1-4 of 4
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Characterization and analysis of repetitive centromeres
Kasinathan, SivakanthanCentromeres are specialized regions of eukaryotic chromosomes that ensure faithful transmission of genetic information at each cell division. The molecular architecture of centromeres is defined by evolutionarily dynamic ... -
Chromatin landscape of the "dark matter of the genome": centromeres of S. cerevisiae and repeat sequences of D. melanogaster.
Krassovsky, KristinaThe chromatin landscape plays a major role in defining cell phenotypes through transcriptional regulation and specification of the main features of chromosome, such as centromeres and pericentric heterochromatin. Studies ... -
High-resolution studies of the chromatin and transcription landscape
Weber, Christopher MichaelTranscription from genomic DNA is regulated in many ways and governs cellular identity, growth, and homeostasis. If transcription becomes deregulated, it can serve a critical role in the development of cancer and other ... -
Twists and Turns of Transcription: Dynamic interplay between RNA Polymerase II and the nucleosome
Teves, Sheila (2013-11-14)Transcription regulation underlies basic processes essential to life, including differentiation and development, cell-to-cell communication, and response to environmental stimuli. How the cell achieves a precise gene ...