Browsing Molecular and cellular biology by Author "Bierle, Craig John"
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Inhibition of the protein kinase R pathway by cytomegalovirus double-stranded RNA binding proteins
Bierle, Craig John (2013-04-17)Double-stranded RNA (dsRNA) that accumulates during many viral infections is recognized by the host cell and elicits an antiviral response. Protein kinase R (PKR) is activated by dsRNA binding, phosphorylates eIF2α, and ...