LAGLIDADG Homing Endonucleases (LHEs) are a family of highly specific DNA-cutting enzymes capable of recognizing target sequences of ~20 bp. In many eukaryotes, including humans and yeast, double-strand breaks induced by ...
Targeted genome engineering is a technology that has the potential to vastly improve clinical medicine, as well as biological research. With the ability to design enzymes targeting any given DNA locus of interest, and ...