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The identification and characterization of acute kidney injury (AKI) associated with systemic polymyxins in the management of severe gram-negative infections
Background The global rise in antibiotic resistance has led to an increased need for effective antimicrobial treatments. Polymyxins have re-emerged in recent years due to their strong antimicrobial activity against resistant gram-negative pathogens. However, there is concern of renal toxicity associated with the use of ...