Browsing Pharmacology by Subject "Arrestin; c-Jun N-terminal kinase; Fentanyl; Morphine; Opioid; p38"
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Mechanisms of Opioid Receptor Desensitization
Agonists targeting MOR are effective analgesics, but their clinical use is hindered by side effects, including tolerance and addiction. KOR agonists also produce analgesia, but clinical use of these compounds has remained ...