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Biological nanopore MspA for DNA sequencing
Unlocking the information hidden in the human genome provides insight into the inner workings of complex biological systems and can be used to greatly improve health-care. In order to allow for widespread sequencing, new technologies are required that provide fast and inexpensive readings of DNA. Nanopore sequencing is a ...
Measuring how lipid membranes respond to physical perturbations: How charge alters lipid miscibility, how shear disrupts interleaflet coupling, and how prebiotic compounds affect membrane stability
The physical and chemical properties of lipid bilayers determine their biological function as the main structural component of cell membranes. The response of lipid membranes to various perturbations is, in general, difficult to predict. This dissertation will discuss four sets of experiments to probe the behavior of lipid ...