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T6SS in Pseudomonas aeruginosa: A novel model for toxin delivery
The Type Six Secretion System (T6SS) is a bacterial toxin-delivery system targeting bacterial cells which neighbor the donor, promoting recipient cell death. The T6SS is widely conserved among Gram-negative bacteria and may be a central determinant in bacterial fitness in polymicrobial communities of particular relevance to ...
Probabilistic Neural Coding from Deterministic Neural Dynamics: mathematics and biophysics of adaptive single neuron computation
The basic unit of computation in the nervous system is the transformation of input into output spikes performed by an individual neuron. The spiking response of the neuron to a complex, time-varying input can be characterized with two different classes of models: nonlinear dynamical systems represent the detailed biophysical ...