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Browsing Physiology and biophysics by Title
Now showing items 21-26 of 26
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Spatial distribution of ventilation and perfusion in the lateral decubitus posture
(2001)Pulmonary blood flow distribution is affected by many factors, including gravity, hypoxic pulmonary vasoconstriction (HPV), lung volume and positive end-expiratory pressure (PEEP). In the lateral posture, the effects of ... -
Spike-timing dependent plasticity and connectivity in primate sensorimotor cortex
Specific connectivity between populations of neurons gives rise to network function. The plasticity of these connections allows for network learning and adaptation. While much work has explored plasticity and underlying ... -
Summation of AMPA-mediated EPSPs in rat neocortical pyramidal neurons
(1998)It has been hypothesized that voltage-sensitive conductances present on the dendrites of neurons can influence the summation of EPSPs and hence affect how neurons compile information. Greater than linear summation of EPSPs ... -
The mechanisms and applications of a nucleotide-based heart failure therapy
The naturally-occurring nucleotide 2-deoxy-ATP (dATP) is known to increase the amount of force produced by cardiac muscle when used as a substrate in place of ATP. Cytosolic concentration of dATP can be elevated by expressing ... -
The Mechanisms Underlying Sigh Generation in the PreBötzinger Complex are Dependent on Neuroglial Interactions
Rhythm generation is a vital component of life. Rhythmic activity regulates the circadian clock, which controls hormonal cycles, sleep wake states, blood pressure, body temperature, and reaction times. Rhythmogenesis ... -
Three lenses into the cardiac dyad: calcium signaling, microtubule trafficking, and junctional sarcoplasmic reticular mobility
The cardiac dyad, the intersection between the sarcoplasmic reticulum and the sarcolemma in cardiac myocytes, is critically important for cellular contraction and function. It is the hub of calcium signaling where ryanodine ...