Lalic, GojkoChen, Jason2019-08-142019-08-142019-08-142019Chen_washington_0250O_19981.pdfhttp://hdl.handle.net/1773/44113Thesis (Master's)--University of Washington, 2019Chapter 1 describes the stereospecific synthesis of E-alkenes through a dual copper and nickel catalysis system involving terminal alkynes and primary and secondary alkyl iodides. This reaction proceeds with excellent anti-Markovnikov and diastereoselectivity and is compatible with a wide range of functional groups. This hydroalkylation reaction allows easy access to a variety of E-alkenes from simple and readily available alkyne precursors.application/pdfen-USnoneChemistryOrganic chemistryChemistryThesis