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The expression of neural and developmental genes in Pleurobrachia bachei
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Date
2012-10Author
Mahone, Ian
Swalla, Billie J.
Kohn, Andrea
Moroz, Leonid
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Show full item recordAbstract
Brachyury and Forkhead are transcription factors that play an important role for
development within organisms. Ctenophores are basal metazoans with little known
about what kind of gene they have or where these genes are expressed. For these
reasons, brachyury and forkhead are used as a markers in the ctenophore
Pleurobrachia bachei. These genes were cloned and then used for in situ
hybridizations in adults. This revealed distinctive expression patterns for brachyruy in
the esophagus and stomach, while forkhead was expressed in the tentacles and combs
rows of the animal. Not to mention, that through genomics and bioinformatics the
forkhead genome has been discovered. Revealing that there is 24 forkhead genes
within the genome of ctenophores.