Type I IFN, Toll-like Receptor Signaling and Myeloid Homeostasis
Buechler, Matthew Bryan
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The roles of toll-like receptor and type I interferon signaling in modulating myeloid homeostasis are incompletely defined. Here, we investigate how these factors interact to influence myeloid development in the bone marrow and myeloid cell egress from the bone marrow. The findings described here advance our knowledge of basic immunology and may have clinical applications in the contexts of autoimmunity and infection.
- Immunology