Ophthalmic Application of Optical Coherence Tomography Angiography for Retina and Choroidal Imaging

Abstract

Optical coherence tomography (OCT) angiography (OCTA) is a revolutionary non- invasive imaging modality that has been widely utilized in ophthalmology. OCT and OCTA has huge potentials for quantitative analysis based on its ability of detecting high-resolution three-dimensional data. In this thesis, the capacity of OCT detecting choroidal vasculature was demonstrated and techniques to quantify choroidal lesion character was described and showed advantages when compare to other imaging techniques. Also, vascular quantification tools for retina and choroidal microvasculature with different subregional analyze were proposed and tested on clinical OCTA system data of diseased subjects. Overall, the thesis presents a set of tools that can extract features from human ocular vasculature and generate regionally and quantitatively analysis.