Cortical Stimulation Induces White Matter Plasticity Following Spinal Cord Injury

Abstract

This thesis describes experiments conducted to elucidate the potential for neuromodulation to induce white matter plasticity in the spinal cord injured rat. In addition, it highlights experiments designed to address the effect of neuromodulation on additional sequalae of spinal cord injury. Potential experiments are proposed to address the mechanisms by which the injured spinal cord responds to neuromodulation and the contribution of white matter plasticity to other facets of spinal cord injury and recovery.