Parsing for Differences between Lck and Src Members

Abstract

There are hundreds of kinases that have been identified and grouped within eukaryotic organisms and one specific family of these kinases are known as Src Family Kinases (SFKs). A unique trait about SFKs is the large similarity amongst them yet they exhibit non-redundancy in their specialized roles – and one of these members, Lck, is specifically involved with immune response involving T-cell receptors. Understanding what differentiates Lck from the rest of the SFKs would provide insight into how SFKs serve specialized roles and potentially be used towards immunological applications.