Templates for Automated Fiber Quantification of human corpus callosum from Diffusion MRI data

Abstract

These templates are used to segment human white matter into the major tracks, as described in Yeatman et al. 2012 (Yeatman JD, Dougherty RF, Myall NJ, Wandell BA, Feldman HM (2012) Tract Profiles of White Matter Properties: Automating Fiber-Tract Quantification. PLoS ONE 7(11): e49790. doi:10.1371/journal.pone.0049790). Briefly, The regions of interest (ROIs) in these templates are defined in locations that isolate the central portion of the track where the fibers are coherently bundled together and before they begin diverging towards cortex. Each waypoint ROI was drawn on a group-average DTI data set in MNI space based on the anatomical prescriptions defined in Wakana et al (Wakana S, Caprihan A, Panzenboeck MM, Fallon JH, Perry M, et al. (2007) Reproducibility of quantitative tractography methods applied to cerebral white matter. Neuroimage 36: 630–644. doi: 10.1016/j.neuroimage.2007.02.049).